Estradiol is a hormone replacement therapy (HRT).
It contains the female sex hormone estrogen.
Estradiol is used in postmenopausal women whose last menstrual period (menopause) was at least 12 months ago.
Estradiol is used:
Relief of postmenopausal symptoms
During menopause, a woman’s production of her own estrogen decreases. This can cause symptoms such as hot flashes in the face, neck, and chest (called hot flashes). Estradiol relieves these symptoms that occur after menopause. Estradiol will only be prescribed if your symptoms significantly affect your daily life.
Prevention of osteoporosis
After menopause, some women’s bones may become brittle (osteoporosis). You should discuss all available treatment options with your doctor.
You may use estradiol to prevent the development of osteoporosis after menopause if you are at increased risk of osteoporosis-related bone fractures and other medications are not suitable for you.
Experience in treating women over 65 years of age is limited.
The medicine cannot be taken
if the following points apply to you. If you are unsure whether this is the case, consult your doctor before taking estradiol.
You should not take estradiol if
You have, have had, or are suspected of having breast cancer.
You have a form of cancer that depends on estrogen to grow, for example. B. Cancer of the uterine mucosa (endometrium) or suspected
Vaginal bleeding of unknown cause occurs.
Untreated excessive thickening of the lining of the uterus (endometrial hyperplasia).
You have or have previously had a blood clot in a vein (thrombosis), for example. B. in the legs (deep vein thrombosis) or in the lungs (pulmonary embolism)
You have a bleeding disorder (such as protein C deficiency, protein S deficiency, or antithrombin deficiency)
You have or have ever had a condition caused by blood clots in your arteries, such as: B. Heart attack, stroke, or attacks of chest pain with a feeling of tightness in the chest (angina)
You have or have ever had liver disease and your liver function tests have not yet returned to normal.
You have a rare inherited blood disorder called porphyria.
You are allergic to estradiol or any other ingredient of this medicine.
If any of the above diseases occur for the first time while taking estradiol, stop treatment immediately and consult a doctor immediately.
Always take this medication exactly as your doctor has told you. If you are unsure, consult your doctor or pharmacist.
The recommended dose is
1 film-coated tablet per day.
If you have had your uterus removed or no longer have periods, you can start treatment any day.
If you have not had your uterus removed, treatment with estradiol must be combined with a progestogen for at least 12 to 14 days in a 28-day cycle.
The addition of a progestogen is not recommended for women who have had their uterus removed, unless colonization of the uterine lining outside the uterus (endometriosis) has been diagnosed.
If you have previously taken other HRT medications, ask your doctor or pharmacist when you should start taking estradiol.
If you experience breakthrough bleeding or spotting, this is usually not a cause for concern, especially during the first few months of taking HRT.
Your doctor will try to give you the minimum dose needed to treat your symptoms for the shortest time possible. Please talk to your doctor if you think the effects of estradiol are too strong or too weak.
Duration of use
The duration of use will be determined by your doctor.
If you are scheduled for surgery
If you are scheduled for surgery, tell your surgeon that you are taking estradiol. You may need to stop taking estradiol 4 to 6 weeks before your scheduled surgery to reduce the risk of thrombosis. Ask your doctor when you can stop taking estradiol.
If you took more than you should
Possible signs of overdose: nausea, vomiting, breast tenderness and vaginal bleeding. Any treatment that may be necessary should be based on symptoms.
If you take more than that, you should consult your doctor.
If you forget to take it
If you forget to take the film-coated tablet at your usual time, take it within the next 12 hours. If more than 12 hours have passed, do not take the missed film-coated tablet in addition to the next one. Continue treatment as usual. It is possible that breakthrough bleeding or spotting may occur if you do not take the pills regularly. If therapy is interrupted for a longer period, tell your doctor.
If you stop taking it
Do not interrupt or stop treatment with estradiol without consulting your doctor. When stopping, expect withdrawal bleeding.
If you have any more questions about taking this medicine, talk to your doctor or pharmacist.
