Sprycel 80mg, 30, Bristol-Myers

indication
This medicine contains the active ingredient dasatinib. This medicine is used to treat leukemia in adults, adolescents, and children over 1 year of age with chronic myeloid leukemia (CML). Leukemia is a cancer of the white blood cells. These white blood cells usually help the body fight infections. In people with chronic myeloid leukemia, white blood cells, also called granulocytes, begin to grow out of control. The medicine inhibits the growth of these leukemic cells.
The drug is used to treat acute lymphocytic leukemia (ALL) with the Philadelphia chromosome (Ph +) in adults, adolescents and children from 1 year. It is also used in adults with CML for lymphocytic blast crisis who are not responding to previous therapy. White blood cells, also called lymphocytes, multiply too quickly and live too long in people with ALL. The medicine inhibits the growth of these leukemic cells.
If you have any questions about how this medicine works or why this medicine was prescribed for you, ask your doctor.
contraindication
The drug should not be taken
if you are allergic to dasatinib or any of the other ingredients of this medicine.
If you may be allergic, seek the advice of your doctor.
Dosage of Sprycel
The drug will be prescribed only by a doctor who has experience in the treatment of leukemia. Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. The medicine is prescribed for adults and children over 1 year old.
The recommended starting dose for adult patients with chronic phase CML is 100 mg once daily.
The recommended starting dose for adult patients with accelerated or blast phase CML or Ph+ ALL is 140 mg once daily.
Dosing for children with chronic phase CML or Ph+ ALL is based on body weight.
The drug is taken orally once a day, either as film-coated tablets or as a powder for oral suspension.
Film-coated tablets are not recommended for patients weighing less than 10 kg.
Powder for suspension for oral administration should be used for patients weighing less than 10 kg. When switching from one drug to another (for example, tablets and powder for oral suspension), a dose change may be required, so you should not switch from one drug to another.
Depending on your weight, side effects and response to treatment, the doctor will select the correct composition and dose. The initial dose for children is calculated based on body weight as follows:
Body weight 10 to less than 20 kg: 40 mg (daily dose)
Body weight 20 to less than 30 kg: 60 mg (daily dose)
30 to less than 45 kg body weight: 70 mg (daily dose)
body weight at least 45 kg: 100 mg (daily dose)
Tablets are not recommended for patients weighing less than 10 kg. For these patients, the powder should be
use as a suspension for oral administration.
There are no recommendations on the dosage of the drug in children under the age of 1 year.
Depending on how you respond to treatment, your doctor may recommend a higher or lower dose, or even stop treatment for a short time. Higher or lower doses may require a combination of tablets of different strengths.
You can get tablets in calendar packs. These are blisters indicating the days of the week. The arrows point to the next pill to take according to your treatment plan.
How long should the medicine be taken?
Take the drug every day until your doctor tells you to stop. Make sure you take the supplement for as long as it is prescribed to you.
If you take more than you should
If you accidentally take too many tablets, contact your doctor immediately. You may need medical attention.
If you forget to take a dose
Do not take a double dose to make up for a missed dose. Take your next dose at the usual time.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
patient records
Warnings and Precautions
Please talk to your doctor or pharmacist before using the drug,
if you are taking medicine to thin your blood or prevent blood clots
if you have or have had liver or heart problems
if you have trouble breathing, chest pain or cough while taking this medicine: this may be a sign of fluid in your lungs or chest (more common in people over 65 years of age) or due to changes in your blood. vessels lining the lungs supplying
if you have or may have had hepatitis B infection in the past. This is important because the drug can cause hepatitis B to reactivate, which can be fatal in some cases. Before starting treatment, doctors carefully evaluate patients for signs of this infection.