Pharmacological action
A hypnotic drug from the group of cyclopyrrolone derivatives. “Non-benzodiazepine” agonist of benzodiazepine receptors. It also has sedative, anxiolytic, central muscle-relaxant, anticonvulsant and amnestic properties. Like benzodiazepine derivatives, zopiclone enhances GABA-ergic processes in the brain by interacting with benzodiazepine receptors, as a result of which the sensitivity of GABA receptors to the mediator increases. However, zopiclone apparently interacts with other areas of the benzodiazepine receptor than benzodiazepines.
Zopiclone shortens the time it takes to fall asleep, reduces the number of night awakenings, and increases the total duration of sleep. It has virtually no effect on the structure of sleep, and does not significantly reduce the amount of REM sleep. The effects of consequences upon awakening are absent or weakly expressed. Repeated doses of zopiclone are not accompanied by cumulation.
Indications for the active ingredients of Zopiclone-Lekpharm
Sleep disorders (difficulty falling asleep, frequent night awakenings, early awakening), transient, situational and chronic insomnia; sleep disorders in mental disorders; bronchial asthma with night attacks (in combination with a single daily dose of theophylline).
Contraindications for use
Severe respiratory failure, pregnancy, lactation (breastfeeding), childhood and adolescence under 15 years, hypersensitivity to zopiclone.
Warning: Always consult a doctor before using medications.
